ksm66 ashwagandha, ksm-66, ksm-66 ashwagandha

KSM66: The Best Ashwagandha?

Last modified on April 1st, 2024

KSM66 ashwagandha, also known as KSM-66 ashwagandha, is a specific type of incredibly popular herbal supplement. It is often marketed as the most effective ashwagandha. It’s a branded, full-spectrum extract.

The extract comes only from the major roots, and a proprietary extraction process is used to make it.

No alcohol or chemical solvent is used in the production of KSM66.

Since only root is used in the product with no leaves, the makers claim it’s the highest concentration available.

What is Ashwagandha?

Before going into more specifics about KSM66 (KSM-66 ashwagandha), what is general? Ashwagandha, or withania somnifera, is an evergreen shrub grown in parts of the Middle East, Africa, and India. Withania somnifera is also known as Indian Winter Cherry or Indian Ginseng.

The herbal remedy has a long history of use in ancient Ayurvedic medicine.

In Ayurveda, ashwagandha reduces inflammation, pain and anxiety, increases energy, and boosts overall health.

Ayurveda is the traditional medicine system found in India. Ayurveda is a healing medicine that balances the mind, body, spirit, and environment.

When you’re experiencing stress, your cortisol levels rise, your heart might pump faster in response, your breathing speeds up, and your body generates glucose, giving you a burst of energy to deal with the stress. Your body and mind are in fight-or-flight mode. After a stressful event passes, most people’s cortisol levels normalize, and the symptoms get better. Unfortunately, your response is also chronic if you’re experiencing ongoing stress.

Long-term, chronic stress leads to inflammation, raises the risk of developing chronic conditions like obesity, and impacts mental health. Ashwagandha can help stabilize and normalize cortisol levels and reduce your stress response. This is one of the main reasons people take ashwagandha, but there are others.

Benefits of ashwagandha include:

  • Improves athletic performance
  • Increases muscle strength
  • Reduces depression symptoms
  • Boosts testosterone and fertility in men
  • Lowers blood sugar levels
  • Lowers inflammatory markers
  • May help brain function, including memory
  • Boosts mood
  • Better sleep quality

Ashwagandha is also considered a safe herbal supplement for most people, with minimal side effects. Of course, you should speak to your healthcare provider because while it’s safe for most people, ashwagandha might not be safe for everyone.

What is KSM66 Ashwagandha?

Features of KSM66 ashwagandha that make it unique include:

  • KSM66 is a branded full-spectrum extract
  • The highest concentrations of major root-only extracts are available
  • Made without alcohol or any chemical solvent
  • The proprietary extraction process is based on Green Chemistry principles
  • No leaves are used—based on research, the root is the most powerful part of the plant for health benefits. The root of the plant has more scientific evidence to back up its benefits

KSM66 is full spectrum, meaning that it has a balance of the original herb’s constituents without overrepresentation of any one constituent.

The effectiveness of ashwagandha for mental and physical health is thought to come from its complex blend of active constituents.

All of these must be present in natural proportions for the full effects to occur, but it’s hard to produce a high-concentration full-spectrum extract. Only the Ixoreal company has created a process to overcome the challenges other ashwagandha manufacturers face.

The Green Chemistry processing approach used to make KSM-66 allows for a holistic extraction of all the root essences while maintaining its natural healing strength.

What is the Difference Between KSM66 and Ashwagandha?

Key differences between KSM-66 and ashwagandha include:

  • Most ashwagandha extracts range from 1.5-3% active compounds. KSM-66 has concentrations of around 5%.
  • KSM-66 is the highest concentration of full-spectrum root extract.
  • Since KSM-66 is full-spectrum, it doesn’t lose the balance of natural constituents when making other types of ashwagandha.
  • Many types of ashwagandha are made with chemical solvents or alcohol during the extraction process, but KSM-66 is made with milk. This is true to Ayurvedic tradition and neutralizes the bitterness that can come with regular ashwagandha.
  • More studies are backing up the particular benefits of KSM-66 than other types of ashwagandha. For example, studies suggest it may help reduce stress and anxiety, improve thyroid regulation and have anti-cancer properties. Research indicates it could also increase cognitive abilities and memory.

KSM66 Ashwagandha Benefits

The benefits of KSM-66 ashwagandha can include:

  • Reduces anxiety and stress
  • Improves sleep quality
  • Lowers cortisol
  • Combats food cravings
  • Improves cognitive function
  • Boosts memory
  • Helps with endurance and strength
  • Enhances libido
  • May raise testosterone levels in men

Is KSM-66 Ashwagandha Better?

Overall, when comparing types of ashwagandha, there is evidence that KSM-66 is better than other types. Reasons KSM-66 ashwagandha is better include:

  • No leaf components: This type of ashwagandha is made only with roots, and no leaves are added for maximum clinical effectiveness. Most human studies are only on ashwagandha made with the root, not leaf extracts.
  • Negligible levels of withaferin A: Not all withanolides, the medicinal compounds in ashwagandha, benefit human consumption. Withaferin A is potentially cytotoxic, and KSM-66 leaves this withanolide out of the formulation. Some ashwagandha products will have high levels of Withaferin A because leaves from the ashwagandha plants are used. This isn’t an optimal formulation for human health.
  • Optimal withanolide content: When someone chooses an ashwagandha extract, the content of withanolide needs to be too high or too low. When the percentage of withanolides is more than 25%, the extract can be more like a pharmaceutical drug. If the percentage is too low, which would be less than 2.5%, you need a higher dose for benefits. The unique extraction process of KSM-66 allows for the optimum percentage of withanolides. The plant’s bioactives are retained for efficacy.
  • Full-spectrum: Plant-based supplements are complex, with many constituents. Modern research doesn’t always identify which constituents are most beneficial for human health. Many herbalists and scientists think there isn’t one constituent in ashwagandha that makes it so beneficial. Instead, they think it’s the synergistic combination of many. That’s why it’s so critical to use a full-spectrum extract. KSM-66 is a full-spectrum extract, so all the constituents are included in a balanced way.

Is KSM-Ashwagandha Safe?

KSM-66 ashwagandha and most other ashwagandha extracts are considered exceptionally safe. They aren’t FDA-regulated products, though, since they are supplements, so you must research brands and quality.

Ashwagandha is considered safe when taken orally, but large doses could lead to some side effects. Taking ashwagandha when pregnant is considered unsafe because it can raise the risk of miscarriage.

Ashwagandha can also be unsafe for people with thyroid disorders, and people with certain autoimmune diseases might want to talk to their doctor before taking KSM66 or any other ashwagandha extract.

Medications that could interact with KSM-66 ashwagandha include:

  • Immunosuppressants
  • Sedatives like benzodiazepines
  • Thyroid hormone pills
  • Diabetes medications
  • High blood pressure medicines

Ashwagandha KSM-66 Side Effects

Ashwagandha KSM-66 side effects are rare and typically only occur in people who take very large doses. Large doses can lead to:

  • Nausea
  • Vomiting
  • Diarrhea
  • Stomach upset
  • Excessive immune system activity
  • May slow down the central nervous system
  • Could increase thyroid hormone levels

Final Thoughts

KSM-66 is a branded ashwagandha made in a proprietary way that gives it many benefits over other extracts. KSM66 is worth trying whether or not you have experience with other ashwagandha extracts.

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Ashley Sutphin Watkins
Ashley Sutphin Watkins is a graduate of the University of North Carolina at Chapel Hill. She's a medical content writer, journalist and an avid researcher of all things related to health and wellness. Ashley lives near the Smoky Mountains in East Tennessee with her family.
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