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best supplements for leaky gut, leaky gut supplements, heal leaky gut naturally

8 Leaky Gut Supplements

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Last modified on January 25th, 2023

You aren’t alone if you’re looking for the best supplements for leaky gut. Leaky gut supplements can help reduce inflammation in the gut and combat some of the symptoms of this syndrome. The following provides an overview of what supplements to take for leaky gut and other information you should know if you struggle with leaky gut.

What Is Leaky Gut?

The concept of a leaky gut has gotten a lot of attention lately, especially in the world of natural and holistic health. Leaky gut is a condition in which you have increased intestinal permeability. Essentially, when you have this digestive condition, it means toxins and bacteria might be able to leak through your intestinal wall.

Despite the fact there’s growing attention in the natural health world about leaky gut, mainstream healthcare providers often don’t recognize the condition.

Even so, there is mounting evidence that a leaky gut is an actual condition that can have far-reaching effects on a person’s health and well-being.

Your digestive tract is responsible for breaking down food and absorbing nutrients so they can be utilized, and it also protects you from harmful substances. Your intestine walls are barriers to what is transported to your organs via your bloodstream.

Your intestinal wall has areas that allow water and nutrients through while they are supposed to block harmful substances.

When discussing leaky gut, the term intestinal permeability is one you may often hear because it’s a way to describe how easy it is for substances to pass through your intestine wall.

If the junctions of your intestinal wall, which are the areas that let water and nutrients through, are too loose, you’ll have more gut permeability. That can allow the “bad stuff,” such as toxins and bacteria, to move from the gut to the bloodstream, thus creating a leaky gut.

When you have a leaky gut, it can cause a possible immune response, and it can lead to inflammation throughout your body.

According to Harvard Health, the intestinal lining covers more than 4,000 square feet of surface area. When an unhealthy gut lining exists, it can allow things to penetrate the tissues below that gut lining leading to changes in the normal bacteria or gut flora.

Harvard points out that there are several studies happening right now that look at the links between intestinal bacteria and inflammation in the development of chronic diseases.

What are the Symptoms of a Leaky Gut?

Symptoms of leaky gut can be broad and may include:

  • Bloating
  • Food sensitivities
  • Skin problems
  • Fatigue
  • Digestive issues

Specific things that could be linked to a leaky gut also include:

  • Irritable bowel syndrome
  • Brain fog or problems concentrating
  • Depression or anxiety
  • Eczema or similar skin issues
  • Asthma or seasonal allergies
  • Hormonal imbalances

Some people believe leaky gut is linked to a wide variety of conditions, such as:

  • Chronic fatigue syndrome
  • Migraines
  • Fibromyalgia
  • Food sensitivities
  • Mood disturbances
  • Skin conditions
  • Thyroid problems

While this may very well be true, there is currently limited research on leaky gut syndrome. Traditional healthcare providers may be unaware of the issues surrounding a leaky gut or unwilling to offer a diagnosis until more is officially known.

What we do currently know is that having more intestinal permeability can be part of certain gastrointestinal conditions like:

  • Irritable bowel syndrome
  • Celiac disease
  • Crohn’s disease

What’s currently less understood is how gut permeability might play a more significant role in physical and mental health and conditions such as autoimmune diseases.

What Causes Leaky Gut?

Harvard Health’s resources on leaky gut say that, to an extent, it affects us all because our intestinal barrier isn’t entirely impenetrable, nor should it be.

However, genetic links may make some of us more sensitive to changes in our digestive system than others.

Elements of modern living may also play a role in the development of inflammation in the gut and leaky gut syndrome.

For example, the standard American diet, which tends to be high in sugar and saturated fat and low in fiber, may begin the process of a leaky gut. Stress and alcohol use may also be factors.

Much like other things surrounding leaky gut, specific causes of the condition aren’t entirely understood, but there are some theories.

Possible contributors to increased intestinal permeability may include:

  • Chronic inflammation throughout the body
  • Consuming too much sugar which can damage how the intestinal wall functions
  • Taking non-steroidal anti-inflammatory drugs (NSAIDs) for a long time
  • Excessive alcohol
  • Being deficient in specific nutrients, including A, D, and zinc
  • Chronic stress, which is linked to a variety of gastrointestinal disorders
  • Disruptions in the balance of harmful and beneficial bacteria in the gut
  • An overgrowth of yeast

Is Leaky Gut a Symptom of Disease, Or a Disease Itself?

With so much still unknown about leaky gut and intestinal permeability, it’s natural to question whether it’s in and of itself a disease or a symptom of other diseases.

What we know is that with chronic disease and, in particular autoimmune diseases, intestinal permeability is frequently seen. However, we don’t know whether it’s the cause or, again, a symptom of them.

In animal studies looking at conditions like celiac disease, there has been some evidence intestinal permeability existed before the onset of the disease. The same was true in other animal studies examining type 1 diabetes and IBS.

At the same time, in people with celiac disease, their level of intestinal permeability frequently returned to normal once they followed a gluten-free diet for more than a year. That would show that the problems with intestinal permeability would be linked to gluten ingestion rather than being a reason for celiac disease.

How Can You Improve the Health of Your Gut?

You can make plenty of lifestyle changes if you feel your gut balance is off or you have leaky gut syndrome. Even having specific digestive symptoms, such as bloating, might be aided by making simple changes. We’ll go into the best supplements for healing leaky gut, but generally, consider doing the following:

Eat a Diverse, Healthy Diet

Bacteria grow in your intestines—hundreds of species.

Each specific bacteria growing in your stomach plays different roles in your health and needs certain nutrients to thrive. If you have a diverse set of bacteria in your stomach, then that’s considered to be a marker of good gut health.

Eating different, varied, and healthy foods can help promote better bacteria health in your gut.

Unfortunately, the typical American and western diets are low in diversity and abundant with fat and sugar.

Focus on eating many fruits, vegetables, beans, nuts, and other items.

Fruits and vegetables are among the best nutrient sources for healthy gut microbiota; they’re rich in fiber and fiber and can help stimulate the growth of some of the bacteria in your gut.

Legumes and beans are also excellent high-fiber choices.

Incorporate Fermented Foods Into Your Diet

Fermented foods undergo a process involving yeasts or bacteria that takes the sugar naturally occurring in food and turns it into acids or alcohol. Fermented foods include kimchi, sauerkraut, kombucha, tempeh, yogurt, and kefir.

Fermented foods tend to have a lot of lactobacilli, which are gut-beneficial bacteria.

For example, when people eat a lot of yogurt, they tend to have high amounts of lactobacilli in their intestines and fewer Enterobacteriaceae, which are linked to chronic diseases and inflammation.

Skip Artificial Sweeteners

Artificial sweeteners like aspartame can cause adverse problems with gut microbiota and adversely impact insulin and blood sugar.

Focus on Including More Plants Into Your Diet

Even if you don’t go vegetarian or vegan, when you have a leaky gut or you feel that you could, it may be a good idea to try and increase the amount of plant-based foods you consume and lower the animal-based foods.

A diet rich in vegetables and plant-based food can help your gut microbiota thrive, perhaps because plant-based foods are high in fiber.

A diet centered around a large amount of diverse plant-based foods may also help reduce cholesterol and inflammation.

Consume Foods with Polyphenols

Polyphenols are certain compounds that doctors and researchers believe have a number of health benefits, such as the ability to help lower blood pressure and inflammation. Some research indicates polyphenols can also reduce oxidative stress.

Sources of polyphenols can include green tea, dark chocolate, red wine, almonds, blueberries, and broccoli.

Polyphenols may help increase good gut bacteria like Bifidobacteria and lactobacilli and reduce harmful bacteria.

Take a Probiotic

A probiotic can be an excellent addition to your supplement routine for most people, even if you don’t think you have symptoms of a leaky gut.

Probiotics can help your gut bacteria stay balanced, especially if you have digestive issues.

Work on Strategies to Reduce Stress

The stress you experience daily can impact every aspect of your health, including your gut health.

Animal studies have shown being psychologically stressed can disrupt the balance of microorganisms in your intestines. Along with psychological stress, environmental stress like excessive noise or sleep deprivation can also impact your gut health.

Work on ensuring you have healthy coping mechanisms in place to deal with stress, try to get enough exercise, and also focus on healthy sleep routines.

What Are the Best Supplements for Leaky Gut?

Many wonder, “what are the best natural supplements to heal inflammation in the gut and leaky gut.”

The following is a breakdown of the best supplements for leaky gut. We based this list of the best supplements for healing leaky guts on a few factors, including product ingredients and claims from manufacturers, reviews from real users, and scientific evidence and research.

heal leaky gut with bone broth, how to heal leaky gut
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Bone broth might not be what you think of as a gut health supplement, but it’s terrific to have in your pantry if you struggle with a leaky gut, issues with your digestive tract, or digestive issues. Our favorite type of organic bone broth for leaky gut is from Left Coast Performance. We like it because:

  • It includes no fillers, sugar, or thickening agents
  • Since this is a bone broth powder, it’s versatile, and you can use it in different ways, including in hot water as soup or even in smoothies
  • Bone broth is believed to have anti-inflammatory agents that can calm the inflammation in the gut
  • Bone broth also has glutamine which can add a “coating” of protection to your intestinal walls and help reduce gut inflammation

Bone broth is something people are increasingly swearing by when it comes to gut-healing foods for the gastrointestinal tract.

You can make your bone broth, but it takes hours, and a lot of dedication, so more people are looking for convenient bone broth supplements, such as the product from Left Coast Performance. Bone broth may have benefits for not only the digestive system but also the joints.

  • Bone broth is made from animal bones and connective tissues and is also nutrient and mineral-packed. For example, brewing bones into a broth will allow them to create calcium, magnesium, and collagen.
  • Collagen helps provide amino acids to the body, a protein building block. Bone broth may also have iron, fatty acids, and zinc.
  • Glutamine is an amino acid found in bone broth that may be especially helpful for healing the gut, which is why we included bone broth on our list of the best supplements for leaky gut. Glutamine supplements were studied, and results were published in 2017 in the journal Current Opinion in Clinical Nutrition and Metabolic Care. Researchers noted that using a glutamine supplement seemed to help heal the intestinal barrier in models looking at animals and humans.

A study published in 2017 in the Nutrients journal showed people with inflammatory bowel disease often have lower levels of amino acids in their body, so there is some evidence to suggest that getting more amino acids could help them. Having bone broth daily can provide amino acids and anti-inflammatory benefits.

There are other possible benefits of bone broth as one of the best supplements for healing leaky gut.

  • For example, a study published in Neuropsychopharmacology in 2015 found that glycine, an amino acid in bone broth, can help improve sleep. It’s possible consuming glycine before going to sleep can improve sleep quality and reduce feelings of fatigue the next day.
  • Bone broth is rich in protein, so it may help reduce your appetite and help you stay fuller for longer, so it could help you lose weight as well.

The Left Coast Performance bone broth supplement is rich in collagen, so it’s a win-win. A serving contains 21 grams of protein, which can help support gut and joint health.

Customer reviews of this product say it has no taste or smell, so it’s easy to add to everything.

Customer reviews say that they enjoy the pure product, which doesn’t have added fillers, and they also see benefits in their personal use, such as increased energy and feelings of strength and stamina.

One review said the person had a bleeding ulcer, and they could heal it with this bone broth.

collagen for leaky gut
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Contains amino acids that can help repair the intestinal wall

Collagen peptides are one of the best supplements to repair leaky gut, with many benefits similar to organic bone broth.

Collagen peptides have amino acids that are vital to repairing the intestinal wall, so they may be able to help with the symptoms of a leaky gut or improve intestinal permeability.

Our favorite personally tried and tested collagen peptide supplement is Great Lakes Gelatin Collagen Hydrolysate.

  • The Great Lakes gelatin product gives you great value because it comes in one-pound canisters, and you can get a discount if you order two packages on Amazon.
  • This product is a good source of pure protein and has no gluten or GMOs.
  • It contains nine specific amino acids and has a high amount of protein.
  • It has no scent or flavor, so it’s easy to add to anything, including your morning coffee, a cup of tea, or a smoothie.

Collagen is a building block of everything in our body; this protein is around 30% of all our proteins. Collagen helps promote the regeneration of connective tissues and is responsible for skin elasticity.

As we age, our bodies produce less collagen naturally, which is why some to supplement with it.

So why is it one of the best supplements for leaky gut specifically?

  • When you use collagen as a supplement, it may help regulate your gastric acids, and some believe it could prevent too much gastric juice from being present in your stomach.
  • Excessive gastric juice is linked to issues such as ulcers and heartburn.
  • There are amino acids that can also help heal the stomach lining.
  • Collagen can help promote better digestion because it helps the intestines break down proteins and carbohydrates, and collagen can help food move through your gastrointestinal system more effectively.

When you take collagen peptides, some research shows collagen synthesis plays a vital role in healing your intestinal lining. Glutamine is also present in many forms of collagen, which can help heal leaky gut and prevent inflammation in the intestinal wall.

Regarding the Great Lakes gelatin version of collagen, we selected it as one of the best supplements for leaky gut for quite a few reasons. First, it’s the collagen product our editor uses daily, combined with coffee, and according to her, it has significantly helped stomach and digestive issues.

Customer reviews of this product say that in addition to helping with digestive and stomach issues, they’ve found other benefits that may have come from using Great Lakes collagen peptides, including the improved appearance of the skin and more joint flexibility.

Some people feel it’s helped them sleep better and promotes hair growth.

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May help reduce inflammation in the gut

Slippery elm is a supplement derived from a tree and a must-have for a healthy intestinal tract.

It has a long history of healing and medicinal uses. For example, Native Americans used it in the 19th century to help heal wounds, and they took it by mouth to help with symptoms of colds and the flu. Our best slippery elm supplement is MicroIngredients’ Organic Slippery Elm Powder. We like this as one of the best supplements for leaky gut because:

  • This slippery elm bark supplement comes as a powder, making it relatively easy to absorb and also economical
  • May help with digestive issues, including inflammation in the gut
  • Reviews say it helps with recovery from winter illnesses and it helps with abdominal pain from various digestive diseases and issues
  • Users say it has a neutral smell and taste and dissolves easily

Slippery elm supplements are not only among the best supplements for leaky gut, but slippery elm has other possible health benefits as well. For example, slippery elm is sometimes used as a supplement to help with diarrhea, cough, acid reflux, constipation, and certain skin conditions.

  • Slippery elm contains something called mucilage, a substance that becomes like a gel when mixed with water.
  • This helps coat the throat, mouth, stomach, and intestines, which is why some people feel it helps with leaky gut and symptoms of Crohn’s disease, ulcerative colitis, and irritable bowel syndrome.
  • There is some evidence that slippery elm might also help with stress and anxiety, and there are links between slippery elm and breast cancer prevention.

Slippery elm supplements are derived from the tree’s inner bark, which can be dried and powdered so that it can be added to a variety of different types of supplements.

Regarding how to use slippery help to help with leaky gut and gut health, the specifics can vary, but it’s usually recommended to take around one to two teaspoons of powdered slippery elm. You can potentially take higher doses as well, and there don’t tend to be a lot of known side effects from slippery elm.

Many people will mix warm or hot water with slippery elm powder.

Based on antidotal reviews from users on Amazon, with the Microingredients organic slippery elm product, benefits include reducing nausea and abdominal pain, improvements with acid reflux, and freedom from symptoms of IBS and similar conditions. This particular product has many five-star reviews.

zinc for leaky gut, how does zinc help with leaky gut, what are the best supplements for leaky gut, zinc and crohn's
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Zinc supplementation may help reduce intestinal permeability which is linked to leaky gut

Zinc is a valuable nutrient that helps the immune system, and zinc is also used by the body to make specific proteins, plus it’s valuable for wound healing.

Our favorite zinc supplement is the Garden of Life Zinc vitamin with vitamin C. We generally feel Garden of Life offers high-quality products, and we like this zinc supplement because:

  • Zinc supplementation has been shown in research studies to help resolve intestinal permeability in people with Crohn’s disease
  • This particular zinc supplement is one of the best supplements for leaky gut because it also contains the RAW veggie mineral blend, which is a combination of 17 vegetables and 75 trace minerals
  • Includes 100% of the DV of calcium as well as 200% of your DV of zinc
  • Includes no binders or fillers, and it may help with immune system function

When it comes to the best supplements for leaky gut and the best supplements for healing leaky gut, zinc has to be included.

  • Zinc is a nutrient we all need for optimal health.
  • Zinc is used to heal wounds, it helps the immune system fight off bacteria and viruses, and it’s needed to make proteins. Zinc is found in foods like oysters, red meat, shellfish, beans, and nuts, but not everyone consumes enough of these foods to get an adequate amount of zinc.
  • Zinc may help reduce symptoms and duration of diarrhea, may help combat infections, and zinc may help prevent or slow the development of certain degenerative eye conditions.

Research shows it reduces intestinal permeability in people with Crohn’s. That study was from 2001, and there was research in 2015 that indicated zinc might help change the tight junctions of the lining of the intestines, which could reduce gut permeability.

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Research shows berberine may have positive effects similar to pharmaceutical drugs

Berberine is a lesser-known gut health supplement for some people, but it positively affects the gut microbiome.

Berberine may also have other health benefits, such as the ability to help lower blood pressure and promote weight loss. Our selection for the best berberine extract is from Toniq. We like this berberine supplement because:

  • This berberine supplement is excellent for helping heal leaky gut, and this particular version is 97% standardized purity
  • 82x concentrated extract for maximum potency
  • Since it is a pure product, it has more bioavailability, meaning you’re going to get the maximum effects from this supplement
  • In customer reviews of the Toniq berberine, customers say it’s the best berberine they’ve ever used, and it’s significantly helped them with their digestive issues and regulation of blood sugar levels

Berberine may not be the most widely known supplement in terms of name recognition, but it can bring powerful health benefits.

For example, evidence suggests berberine can reduce blood sugar, improve cardiovascular health, and help with weight loss. In some studies and for some purposes, berberine is as powerful as pharmaceutical drugs.

Berberine is considered an alkaloid and was long used in traditional Chinese healing and medicine, but science has taken a look at its benefits in modern times as well.

  • When you take a berberine supplement, it is transported into your bloodstream and then to your cells, where it binds to specific molecules and changes how they function.
  • This is how pharmaceutical drugs work, as well. One study from Chinese researchers indicated that berberine could have therapeutic benefits for different chronic diseases, including certain cancers, heart diseases, inflammation, and type 2 diabetes.
  • Researchers concluded that berberine could be part of successfully treating chronic diseases.

One of berberine’s many impressive benefits may be its ability to help with digestive health, along with a slew of other potential positive effects on your health.

  • Berberine can help combat harmful microbes and, in some cases, perhaps even better than antibiotics.
  • Berberine can uniquely target harmful organisms, including in the gut, but leave the healthy and productive bacteria alone.
  • Berberine, for example, can promote the presence of Akkermansia muciniphillia, a beneficial gut bacteria. This bacteria plays a critical role in protecting the intestines from damage. The more of this particular bacteria, the lower the risk of chronic inflammation and metabolic syndrome.
  • A gut bacteria called Bifidobacterium, which reduces the absorption of toxins in the gut and inflammation, can be increased with berberine.

Berberine, along with helping with leaky gut, may help with various inflammatory bowel diseases. In a recent animal study, researchers also looked at using a berberine supplement in rats with nonalcoholic fatty liver disease. The berberine helped reduce changes in the intestinal mucus of the rats studied.

Berberine is a safe supplement; a typical dosage is around 500 mg, taken three times a day before meals. However, as with any supplement, speak to your doctor if you are on a medication to lower your blood sugar.

curcumin for leaky gut, tumeric for leaky gut, best curcumin, benefits of curcumin
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Curcumin is an excellent all-around anti-inflammatory substance

Curcumin is the primary active ingredient in turmeric. Curcumin has powerful antioxidant and anti-inflammatory effects in reducing gut inflammation, and it may prove helpful for people with different digestive disorders, including leaky gut. Our pick for the best turmeric curcumin supplement for leaky gut is from Bio Schwartz.

  • This form of turmeric curcumin has Bioperine, which helps improve absorption significantly—without Bioperine, curcumin isn’t very bioavailable in the human body
  • Gluten and allergen-free formulation and non-GMO ingredients
  • 95% standardized curcuminoids per serving, which is one of the highest potency options available
  • Reviews say it’s helped people with pain from conditions such as fibromyalgia and other chronic conditions

If there’s one supplement that maybe everyone wants to have in their arsenal of natural health products, it’s the curcumin in turmeric.

Among being one of the best supplements to take for leaky gut, curcumin has powerful antioxidant and anti-inflammatory properties.

Curcumin is one of the curcuminoids in turmeric. Curcuminoids are compounds, and turmeric has a long history in cooking and medicine.

Since curcumin is poorly absorbed into the bloodstream, it’s best to have black pepper with it. Black pepper contains something called piperine, a natural substance that can improve the body’s absorption of curcumin by up to 2,000%. Bioperine is the black pepper-derived compound that helps with absorption in the above-recommended turmeric supplement. Anytime you choose a turmeric or curcumin supplement, look for one with piperine or Bioperine. Curcumin is also fat-soluble, so some people take it with a fatty meal to improve absorption.

Researchers believe chronic inflammation can play a role in nearly every chronic disease common in western society.

  • Since curcumin has strong anti-inflammatory properties, it can be helpful in different ways. Curcumin can have the same powerful effects as some anti-inflammatory drugs minus the side effects.
  • Curcumin can also block something called NF-kB. NF-kB is a molecule that travels to cells and is believed to activate inflammation-related genes. It’s also believed that NF-kB is part of many chronic diseases’ development.
  • A review of scientific studies of curcumin found it has the potential to be used to treat many gastrointestinal diseases.
  • In a separate study, curcumin was shown to help improve intestinal barrier function and the organization of the so-called tight junctions that play a pivotal role in intestinal permeability.

One of the reasons curcumin may be so beneficial for digestive disorders, including leaky gut, is because when our body absorbs it, it tends to concentrate primarily in the gut. This allows it to help decrease gut inflammation and promote intestinal barrier health.

If you’re starting your search for the best supplements for leaky gut, turmeric or curcumin can be a good starting point.

glutamine for leaky gut, best supplements for leaky gut, how glutamine helps leaky gut
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Glutamine is a powerful supplement to help repair stomach lining since it's an amino acid.

L-glutamine is also sometimes just called glutamine. This supplement is an amino acid to support gut health and helps promote healthier intestinal barrier function.

Amino acids are the primary building blocks of protein in our body. Our pick for the best glutamine supplement for leaky gut is from Optimum Nutrition.

These muscle recovery capsules are affordable and rank as Amazon’s best-seller among nutritional supplements.

  • This glutamine supplement includes 240 capsules in the package, so you’re getting a good deal with these, and they’re going to last you for quite some time
  • They’re highly concentrated, and each capsule has one gram of pure L-glutamine
  • Many reviewers say they feel glutamine has helped them in several ways, including for leaky gut and other digestive issues and indigestion issues
  • Glutamine is also suitable for helping you stick with a healthy diet because it can alleviate cravings for sweets

Glutamine, according to research, plays an essential role in digestion, absorption, and secretion in the gastrointestinal system. L-glutamine, as the most abundant amino acid in the body, plays an integral role in what’s described as mucosal integrity.

During trauma, such as following surgery, the consumption of glutamine in the small bowel often happens faster than its production rate.

That’s why glutamine is often used to help people following surgery, certain illnesses, or even as a supplement during chemotherapy to protect the tissues in the body. The FDA approves glutamine as a prescription treatment for sickle cell disease. People with severe burns often receive glutamine through a feeding tube to help reduce the risk of developing infections.

Some research shows that glutamine can prevent the movement of bacteria out of the intestine so that they can’t go into other parts of the body following significant injuries.

Even beyond the many potential physical benefits of glutamine, it’s also being looked at for its psychological benefits. For example, there is some evidence that a glutamine supplement could help with symptoms of anxiety and depression, although more research needs to be done on the topic.

L-glutamine can help support the integrity of the gut barrier, and it has other benefits. For example, glutamine can help stabilize blood sugar levels and promote optimal function of the pancreas.

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Boswellia is a powerful inflammation fighter and it may help reduce symptoms of autoimmune disorders.

Boswellia is an extract from the resin of a treat that grows natively in India and the Middle East.

Boswellia is also known as Indian frankincense and has potentially fantastic health benefits. Our pick for the best Boswellia supplement on Amazon is a powdered version from Microingredients.

  • Boswellia powder offers versatility in how you use it—for example, you can mix it into teas or smoothies, take it with a tablespoon of oil to help with absorption, or you can make your capsules
  • Boswellia powder tends to have a higher concentration and be more quickly absorbed than other forms
  • Boswellia is a powerful inflammation fighter, and it can reduce free radical damage in the body
  • Boswellia can interfere with the development of autoimmune diseases because it’s believed to help control the production of antibodies, also known as immunoglobulins

Boswellia comes from a tree, and it’s frequently used in Indian Ayurveda medicine. Also called Indian Frankincense, it’s used for various conditions in traditional medicine, including abdominal pain, rheumatoid arthritis, joint pain, and sometimes even to help with cancer symptoms.

Boswellia is believed to be incredibly beneficial for health because it has compounds that regulate the immune system.

For example, Boswellia might help regulate lymphocytes and white blood cells and regulate the production of immunoglobulin G (IgG) antibodies. It may also help interfere with the production of cytokines, which can raise inflammation in the body.

According to a study published in the Journal of Phytotherapy and Phytopharmacology, Boswellia extract can help treat the pain that comes with osteoarthritis

For people who receive holistic cancer care in addition to their conventional medical care, Boswellia is often used. 

Some evidence suggests Boswellia can help target cancer cells while retaining healthy ones. There may be links between Boswellia and anti-cancer effects, particularly brain, breast, colon, prostate, stomach, and pancreatic cancers. 

Boswellia may help reduce the effects of chemotherapy for people going through cancer treatment also. In a small study, participants taking 400 mg of Boswellia three times a day for six weeks reduced inflammatory bowel disease symptoms. Boswellia might also help with migraines and cluster headaches.

For people with ulcerative colitis, some research shows that Boswellia can induce remission in anywhere from 70 to 80% of people.

As far as autoimmune diseases go, Boswellia can help with chronic bowel diseases, asthma, and arthritis. It appears to control the production of antibodies made by the immune system, and that’s how it’s thought to help with autoimmune disorder symptoms.

In one study, Boswellia was shown to protect the intestinal barrier from oxidative and inflammatory damage, which is one key reason it can be valuable as one of the best supplements for leaky gut.

Final Thoughts—The Best Supplements for Leaky Gut

The above supplements may be good for leaky gut, but many of them have a host of other benefits, including various chronic diseases. We encourage you to research the best supplements for leaky gut, and as always, if you have questions or concerns, consult with a medical professional.

Some other leaky gut supplements to consider include vitamin D and probiotic supplements to help promote good bacteria.

Besides trying supplements for leaky gut, consider changing your diet, which will also support a healthy gut microbiome. You can have gut-healing foods and healthy fats and work towards eliminating low-nutrition processed foods.

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