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Nugenix: What Should You Know?

Last modified on June 9th, 2023

Nugenix is a top-selling men’s health product and testosterone booster, but what’s the truth?

Is it worth it? We answer some of the big questions you may have, like the ingredients and what the Nugenix ultimate reviews from customers say.

Key Takeaways

  • There are several different formulations of Nugenix, including the main Nugenix Free Testosterone Booster, Nugenix Total-T, and Nugenix Ultimate.
  • Regarding customer reviews on Amazon, Nugenix Ultimate is the top-rated product, although the other two options perform pretty well in the reviews.
  • The Nugenix Free Testosterone Booster is made up of a proprietary blend of primarily natural ingredients.
  • A dietary supplement that may boost free testosterone and sex drive.
  • Could help with overall health and vitality as well.

What Is Nugenix?

Nugenix is a free testosterone booster. It’s a dietary supplement, and someone might take it to boost free testosterone and improve their libido and sex drive.

It’s possible that taking Nugenix could help with mild to moderate problems with sexual performance.

The supplement can also help you feel more energetic and may improve your muscle composition when paired with exercise.

There are no stimulants or banned substances in Nugenix, and there’s no caffeine.

Free testosterone is a measure of the unattached testosterone in your blood. Testosterone is made in your adrenal glands and testes. Most testosterone in your blood attaches to two proteins: albumin and sex hormone-binding globulin. If testosterone doesn’t attach to those proteins, it’s free.

Your free testosterone, as well as the testosterone bound to albumin, is known as bioavailable testosterone. Your body can easily use bioavailable testosterone.

For men with low levels of testosterone, also known as hypogonadism, symptoms can include low energy and sex drive, bone loss, and infertility.

Understanding the Difference Between Free and Total Testosterone

When discussing Nugenix ultimate reviews, it can be useful to ensure you know the difference between free T and total T, since Nugenix is specifically intended to boost free testosterone. We touched a bit on this above, but understanding the differences can help you figure out if this product is right for you.

Your body can use free testosterone. Your body can freely use these testosterone molecules because they aren’t attached to protein.

That means free testosterone is incredibly important because the cells can signal to other molecules that regulate your metabolism and other functions.

Since total testosterone measures how much T you have in your blood, total T will always be higher than free T.

What can often happen is that a man will feel like he’s experiencing symptoms of low testosterone (hypogonadism), and then he’ll get his testosterone levels tested. He’ll find out he has normal total T.

The issue may then be that his free T is low. You can have normal levels of total testosterone but still have symptoms of testosterone deficiency.

Nugenix Free Testosterone Booster Ingredients

The following provides an overview of the ingredients in Nugenix Free Testosterone Booster.

Vitamin B6

Vitamin B6 is important for testosterone, and low levels are thought to be associated with low testosterone levels.

Vitamin B6 is also known as pyridoxine, and along with helping promote higher testosterone levels, it can lower the production of estrogen, which is a female hormone.

Vitamin B6 is also integral to the health of your liver, skin, hair, and eyes.

Consuming enough vitamin B6 can help you feel happier and more motivated and help you make faster muscle gains.

Vitamin B12:

Another B vitamin that plays an important role in testosterone levels is B12. Vitamin B12, also known as cobalamin, helps your body use energy from fat and protein when exercising. It also plays a role in many other important chemical reactions in the body.


There are links between zinc deficiency and erectile dysfunction. Zinc helps your body produce testosterone, and deficiency in this mineral is more common than you might think. There was a study in 1996 that found a nearly 75% decrease in testosterone for men after 20 weeks of a low-zinc diet. The study also looked at elderly men taking zinc supplements. With higher zinc intake, their testosterone levels almost doubled. Zinc is also needed for the proper function of your immune system.


One of the key proprietary ingredients in Nugenix is called Testofen, which is a standardized fenugreek extract. Testofen can help support free testosterone levels, boost muscle, and help with sexual desire, according to research.

We were able to find a double-blind, randomized clinical study that looked at Testofen. The study involved 120 healthy men between the ages of 43 and 70.

According to the study, after taking Testofen, the study group saw increases in total free testosterone and serum testosterone when compared to a placebo following 12 weeks of active treatment.

The study described Testofen as a safe and effective way to reduce symptoms of androgen deficiency. The study also reported that it could be a good way to increase serum testosterone and improve sexual function in otherwise healthy middle-aged and older men.

In general, fenugreek may also have numerous benefits, along with helping treat low testosterone.

For example, fenugreek may reduce high blood sugar and has anti-inflammatory compounds. Fenugreek can also reduce cholesterol; in test-tube studies, it has killed certain cancer cells, such as lymphoma.


Tribulus is a plant-based dietary supplement that can improve libido and sexual function and reduce blood pressure and cholesterol.

There is a bit of research-based evidence that Tribulus could have benefits. For example, there was a study of women with type 2 diabetes who took 1000 mg of Tribulus per day. The study found the women taking it had lower blood sugar and cholesterol levels than study participants taking a placebo.

However, studies have not found that Tribulus works to increase testosterone levels in humans.

While Tribulus may not boost testosterone, it could boost libido. There was a study of men with reduced sex drives who took Tribulus (750 to 1500 mg a day for two months). That study found the Tribulus increased their sex drives by 79%.

Results were similar in women with reduced sex drives.

Tribulus may have other benefits, too, such as helping boost the immune system, reducing symptoms of depression, and lowering inflammation.

L-Citrulline Malate

L-citrulline malate is a Nugenix ingredient that serves as an amino acid. Athletes and bodybuilders often use it to improve their performance. It can also help improve liver health and blood flow.

What Are the Benefits of Nugenix?

Possible Nugenix benefits include:

  • Increases in free testosterone
  • Boosts your sex drive
  • May help mild or moderate issues with sexual performance
  • No stimulants
  • No banned substances
  • 82% of users reported increased energy levels
  • 63% of users saw improvements in muscle growth and strength
  • Every bottle undergoes rigorous testing
  • Made under FDA Good Manufacturing Practices
  • Bestselling men’s vitality brand at GNC

What Do Nugenix Reviews from Customers Say?

So what do Nugenix’s ultimate reviews say? First, the majority of Nugenix reviews on Amazon are positive. 53% of users give it five stars, and 17% give it four stars. Some of the benefits and effects cited by Nugenix customer reviews include:

  • Helps with energy levels
  • Users say that Nugenix does boost their libido when taken regularly
  • Some users say Nugenix helps their mental health and their motivation
  • According to Nugenix reviews, some users say they have improved stamina

While the majority of Nugenix reviews are positive, there are also negative reviews. Some of the complaints people have about this product include:

  • For some users, Nugenix didn’t work for them
  • It is pricier than other testosterone-boosting supplements
  • Nugenix doesn’t work on total testosterone, although it’s not meant to—it’s for free testosterone only

One big thing we noticed with the negative reviews vs. positive Nugenix reviews is that the people who took it consistently for six weeks or more seemed to have better results. This seems to be something important to keep in mind. Try Nugenix for at least two months before deciding whether it works for you.

Is Nugenix Safe?

Whether or not Nugenix is safe is something you need to speak with your doctor about. Overall, it’s a popular product and has a good reputation for the most part. The ingredients are mostly natural, and at most, people seem to have symptoms like headaches or nausea if they take Nugenix on an empty stomach.

We couldn’t find any FDA warnings or other information indicating Nugenix isn’t safe.

With that being said, you always need to talk to your doctor before you take a supplement, and that includes Nugenix.

According to the company, they haven’t identified any major side effects in their research.

How to Take Nugenix

You should plan to commit to taking Nugenix for a minimum of six to eight weeks to see how well it works for you. Take three capsules a day with water.

The manufacturer says to take Nugenix on an empty stomach. This part is up to you. Taking Nugenix on an empty stomach may be more effective, but you may experience symptoms like nausea. If that happens, you might consider taking it with a small snack.

Try to combine Nugenix with a resistance training plan for the best results.

If you’re going to work out, you might want to take it 30 to 45 minutes before starting. If you’re not going to work out, you should take Nugenix first thing in the morning.

How Long Does Nugenix Take to Work?

A Related question How long Does Nugenix take to work? From our research, it will likely take anywhere from six to eight weeks for Nugenix to start working. Many people see benefits before that, but you may not see the results if you give up on taking it too early.


  • Well-researched ingredients
  • The top seller among testosterone boosters
  • Helps boost free testosterone, which is what your body uses
  • Thousands of positive reviews
  • Along with boosting free testosterone, may improve overall physical health
  • Ingredients like fenugreek are anti-inflammatory and may have anti-cancer effects
  • Can improve workout results


  • More expensive than similar products
  • Should be taken for at least six weeks to see the results
  • Doesn’t improve total testosterone- just free testosterone

Final Thoughts

If you speak to your doctor and get the green light, we recommend Nugenix for someone experiencing low testosterone symptoms. We like natural ingredients backed up by research. We also like that it focuses on free testosterone, which is the testosterone your body uses.

Note: Always speak to your doctor before using Nugenix or any supplement. This isn’t a substitute for medical advice.


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Our Editorial Process

All of our reviews are completely unbiased. We have an in-depth review and ranking methodology for each of our products. We base our reviews on:

  • Peer-reviewed scientific studies and research
  • Real customer reviews
  • Our own experience using products
  • Price and availability

Whenever possible, we review and rank products that we actually use to provide a better understanding of what you can expect. 

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